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Types of EDS 

Hypermobile EDS (hEDS)

  • Generalized joint hypermobility 

  • Skin findings (mildly stretchy skin, abnormal scars, soft skin) 

  • Tissue fragility (hernias, pelvic prolapse, heel papules)

  • Pain or joint instability 

Vascular EDS (vEDS)

  • Arterial rupture at young age (aneurysm, dissection of artery)

  • Spontaneous rupture of sigmoid colon

  • Uterine rupture in pregnancy

  • Carotid-Cavernous sinus fistula formation 

Cardiac-Valvular EDS (cvEDS)

  • Severe and progressive cardiac-valvular problems

  • Skin changes (stretchy skin, atrophic scars, easy bruising)

  • Hypermobile joints 

Dermatosparaxis EDS (dEDS)

  • Extreme skin fragility

  • Very lax/loose skin 

  • Severe, easy bruising

  • Abnormal facial features 

Brittle Cornea Syndrome (BCS)

  • Thin cornea with or without rupture

  • Early onset progressive keratoconus or keratoglobus

  • Blue Sclerae

Musculocontractural EDS (mEDS)

  • Congenital joint contractures or clubfoot

  • Characteristic facial features 

  • Abnormal skin findings (stretchy skin, easy bruising, fragile skin with atrophic scaring)

Periodental EDS (pEDS)

  • Severe and intractable periodontitis of early onset

  • Lack of attached gingiva

  • Pretibial plaques

Classical EDS (cEDS)

  • Very stretchy skin 

  • Atrophic scarring

  • Generalized joint hypermobility 

Classical-Like EDS (clEDS)

  • Very stretchy skin

  • Generalized joint hypermobility

  • Abnormally easy bruising

  • No abnormal scarring 

Arthrochalaisa EDS (aEDS)

  • Congenital (being born with) both hips dislocated 

  • Severe generalized joint hypermobility 

  • Stretchy skin 

Kyphoscoliotic EDS (kEDS)

  • Low muscle tone at birth

  • Early onset/congenital  kyphoscoliosis 

  • Generalized joint hypermobility with joint instability 

Spondylodysplastic EDS (spEDS)

  • Short stature (progressive in childhood)

  • Low muscle tone

  • Bowing of limbs 

Myopathic EDS (mEDS)

  • Low muscle tone at birth and/or muscle atrophy which improves with age

  • Joint contractures

  • Hypermobility of small joints 

Generalized Hypermobility Spectrum Disorders (G-HSD)

  • Generalized joint hypermobility

  • Musculoskeletal complications

  • Joint pain 

  • Absence of other disorders that may cause symptoms 

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